Particle Size Method Development
It is vital to ensuring that all of the parameters which may influence a particle size measurement have been properly assessed in order to generate realistic, accurate and repeatable data.
For dry powder dispersion, this means, for example, ensuring that the amount of energy (air pressure) used to disperse the sample is appropriate. This can be assessed by use of light microscopy techniques.
For suspension work, the time taken to reach dispersion (and how much ultrasonic energy is required) is equally important, together with the correct choice of suspension fluid.
We have undertaken many method development projects for pharmaceutical